Marrow Cellution by Ranfac MC Ran 11C

The patent pending MARROW CELLUTION™ Bone Marrow Harvesting System overcomes the limitations of a traditional bone marrow needle by allowing the user to aspirate in a measured and controlled manner over a large geography inside the marrow space, while restricting peripheral blood infiltration.

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Marrow Cellution

The Marrow Cellution™ Bone Marrow Aspiration & Cancellous Bone Graft Harvesting System is a novel bone marrow access and retrieval device that incorporates features designed to minimize limitations of traditional trocar needles.

The Marrow Cellution bone marrow harvesting needle produces a resulting bone marrow harvest that is so rich in key progenitor cells that the aspirate no longer has to be manipulated through centrifugation prior to application. Marrow Cellution™ maximizes cell recovery while minimizing peripheral blood infiltration. Because fluid under force follows the path of least resistance, trocar needles with side ports aspirate primarily through the distal end of the cannula. This leads to excessive blood collection, requiring additional manipulation, i.e. centrifugation or chemical separation in a laboratory.

A single puncture with Marrow Cellution™ provides high quality bone marrow aspirate and cancellous bone graft, collected from numerous sites within the marrow geography.

The unique design of the Marrow Cellution™ system offers two key features that are not capable with a traditional needle: • Closed-tip aspiration cannula that restricts aspiration through the side holes of the cannula and away from the channel caused by the tip of the needle, avoiding excess peripheral blood infiltration. • A mechanical means for measured controlled retraction of the aspiration cannula to collect bone marrow aspirate from multiple geographies inside the medullary space with a single puncture.

Marrow Cellution™ accesses aspirate flow collected exclusively laterally as the tip of the aspiration cannula is closed allowing marrow collection perpendicular to and around the channel created by the device. It incorporates technology to precisely reposition the retrieval cannula within the marrow space after each aspiration. These features achieve a clinicians‘ desire for a single entry point.

Marrow Cellution™ allows for easy access through soft tissue and cortical bone. A fenestrated blunt trocar is then introduced to create access for closed-end, side port aspiration stylet. The design minimizes trauma to cancellous bone and marrow, thereby mitigating pooling of peripheral blood. The patent-pending design consists of a closed end stylet which forces aspiration of marrow laterally from the marrow space. The manual rotation of the handle allows the fenestrated stylet to be raised to a desired position in a new level of undisturbed marrow for subsequent aspiration aliquots. From a single stick, Marrow Cellution™ is capable of collecting up to 10ml of high quality bone marrow equivalent or superior to other systems that require additional manipulation steps such as centrifugation or chemical separation in a laboratory.

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Bone Marrow
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Centrifugation
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Puncture

FDA

Cleared

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